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Choosing between NexGard and Simparica Trio is one of the most common decisions dog owners face when shopping for all-in-one flea, tick, and heartworm protection. Both are chewable tablets, both are trusted by vets worldwide — but they differ in some important ways. Let's break down exactly what each product covers so you can pick the right fit for your dog. In this article: What Each Product Actually Covers Key Differences Between NexGard and Simparica Trio Speed of Action and Lasting Effect …