4Cyte vs Antinol: Which Joint Supplement Is Right for Your Dog?

Choosing between 4Cyte and Antinol can feel overwhelming when all you want is a happier, more mobile dog. Both supplements have earned loyal followings, but they work in fundamentally different ways — so the best pick depends on your dog's age, activity level, and joint health needs. This side-by-side comparison of dog joint supplements will help you decide with confidence.

How Each Joint Supplement Works

4Cyte takes a two-pronged approach. Its patented plant-oil extract, Epiitalis®, is designed to support the cells that produce cartilage (chondrocytes), while added green-lipped mussel provides natural anti-inflammatory fatty acids. The idea is to protect existing cartilage and encourage the body's own repair processes.

Antinol focuses almost entirely on managing inflammation. Its key ingredient — PCSO-524®, a concentrated lipid extract from green-lipped mussel — delivers a broad spectrum of omega-3 fatty acids and furan fatty acids. By targeting multiple inflammatory pathways, it aims to reduce joint stiffness and improve day-to-day comfort.

In short, 4Cyte leans toward cartilage support plus inflammation control, while Antinol zeroes in on powerful anti-inflammatory action. Neither is inherently better; they simply prioritise different mechanisms.

Key Ingredients Compared

4Cyte Canine:

• Epiitalis® (plant-oil extract) — supports chondrocyte activity and cartilage maintenance.
• Green-lipped mussel — supplies natural omega-3s for joint comfort.
• Abalone — contributes additional marine-sourced nutrients.

Antinol:

• PCSO-524® (green-lipped mussel oil) — a stabilised, super-critical CO₂ extract containing over 90 fatty acids.
• No added glucosamine, chondroitin, or plant-based actives.

The biggest differentiator in this dog joint supplement comparison is that 4Cyte includes a cartilage-stimulating compound alongside its marine ingredients, whereas Antinol delivers a highly concentrated single-source extract. If you're browsing the full 4Cyte range, you'll notice granule and gel options — each using the same core actives in different delivery formats.

Which Dogs Suit Which Supplement?

Consider 4Cyte if your dog:

• Is a young or middle-aged adult and you want proactive cartilage support.
• Is a large or giant breed predisposed to joint wear.
• Already shows mild stiffness and you'd like both structural and comfort benefits in one product.

Consider Antinol if your dog:

• Experiences noticeable joint discomfort and you want targeted anti-inflammatory relief.
• Is a senior who would benefit from a simple, single-capsule routine.
• Has a sensitive stomach — the small soft-gel capsule is generally well tolerated.

Some owners even use both products together for complementary support. There is no contraindication in combining a cartilage-focused supplement with an anti-inflammatory one, though results will vary from dog to dog.

Format, Taste & Ease of Use

4Cyte Canine is available as oral granules that you sprinkle over food or as a gel syringe for fussier eaters. Most dogs accept the granules readily because of the marine-based flavour. The recommended loading phase typically runs for the first six weeks before transitioning to a maintenance dose.

Antinol comes as a small, olive-shaped soft-gel capsule. You can give it whole as a treat, pierce it and squeeze the oil onto food, or hide it in a piece of cheese. There's no loading phase — you simply give the recommended number of capsules daily from day one.

Both supplements are designed for long-term, ongoing use. Joint support isn't a quick fix; consistency over weeks and months is what delivers visible improvements in mobility and willingness to move. You'll find both products — along with other mobility essentials — when you browse our full dog range.

Frequently Asked Questions

Can I give 4Cyte and Antinol together?

Yes. Because they use different active compounds and target different aspects of joint health, many owners use both side by side. Start with one so you can gauge your dog's response, then add the second if needed.

How long before I see results from either supplement?

Most owners notice improved comfort and willingness to exercise within two to six weeks. Dogs with more advanced joint issues may take longer to show visible changes. Consistent daily dosing is key.

Are these supplements suitable for puppies?

4Cyte is generally recommended for dogs from around 12 months of age, while Antinol can be used in younger dogs — check each product's label for specific guidance. For breeds prone to developmental joint conditions, early supplementation can be a smart preventive step.

Ready to give your dog the joint support they deserve? Explore our 4Cyte collection and the rest of our mobility range, and if you're unsure which supplement to start with, have a quick chat with your vet for personalised advice.